Aktogen

Literature

Asztalos Z., Arora N. and Tully T. (2007) Olfactory Jump Reflex Habituation In Drosophila and Effects of Classical Conditioning Mutations. J. Neurogenet., 21: 1–18. 

Bier E, Reiter LT (2002) Using Drosophila melanogaster to uncover human disease gene function and potential drug target proteins. Expert Opin Ther Targets 6:387--399. 

Braff DL, Geyer MA. Sensorimotor gating and schizophrenia:human and animal model studies. Arch Gen Psychiatry 1990; 47:181–188. 

Braff DL, Swerdlow NR, Geyer MA (1995) Gating and habituation deficits in the schizophrenia disorders. Clin Neurosci 3:131-139. 

Engel JE, Wu CF (1996) Altered habituation of an identified escape circuit in Drosophila memory mutants. J Neurosci 16:3486-3499. 

Garcia CC, Blair HJ, Seager M, Coulthard A, Tennant S, Buddles M, Curtis A, Goodship JA. (2004) Identification of a mutation in synapsin I, a synaptic vesicle protein, in a family with epilepsy. J Med Genet 41:183-6. 

Geyer MA, Krebs-Thomson K, Braff DL, Swerdlow NR (2001) Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl) 156:117-154. 

Godenschwege TA, Reisch D, Diegelmann S, Eberle K, Funk N, Heisenberg M, Hoppe V, Hoppe J, Klagges BR, Martin JR, Nikitina EA, Putz G, Reifegerste R, Reisch N, Rister J, Schaupp M, Scholz H, Schwarzel M, Werner U, Zars TD, Buchner S, Buchner E. (2004) Flies lacking all synapsins are unexpectedly healthy but are impaired in complex behaviour. Eur J Neurosci 20:611-22. 

Harrison PJ, Weinberger DR (2005) Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry10:40-68. 

Smith DP (2002) Novel genomic cDNA hybrids produce effective RNA interference in adult Drosophila. Neuron 33:177-84. 

Lease KA, Hirsh J (2005) A novel method of cocaine delivery to fruit flies using a graphic arts airbrush. J Neurosci Methods 141:89-96. 

Matthews AK, Kaufman TC and Gelbart WM (2005) Research resources for Drosophila: The expanding universe. Nature Reviews Genetics 6:179-193. 

Neckameyer WS (1998) Dopamine and mushroom bodies in Drosophila: Experience-dependent and -independent aspects of sexual behavior. Learning Memory 51:157--165. 

Ogden CA, Rich ME, Schork NJ, Paulus MP, Geyer MA, Lohr JB, Kuczenski R, Niculescu AB. (2004) Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Mol Psychiatry 9:1007-29. 

Pendleton RG, Parvez F, Sayed M, Hillman R (2002) Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster. J Pharmacol Exp Therapeutics 300:91--96. 

Scott R, Bourtchuladze R, Gossweiler S, Dubnau J, Tully T (2002) CREB and the discovery of cognitive enhancers. J Mol Neurosci 19:171-177. 

Sharma P, Keane J, O’Kane CJ, Asztalos Z (2007) Automated measurement of Drosophila jump reflex habituation and its use for large-scale behavioural screens for learning and memory mutants. In Preparation. 

Tickoo S, Russell S (2002) Drosophila melanogaster as a model system for drug discovery and pathway screening. Curr Opin Pharmacol 2:555--560. 

Vawter MP, Thatcher L, Usen N, Hyde TM, Kleinman JE, Freed WJ (2002) Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia. Mol Psychiatry 7:571–578. 

Wittekind NC, Spatz HC (1988) Habituation of the landing response of Drosophila. NATO ASI Series, Vol. H19, (Ed. Spazt, Hertting) 1988:351-368.

Literature

Asztalos Z., Arora N. and Tully T. (2007) Olfactory Jump Reflex Habituation In Drosophila and Effects of Classical Conditioning Mutations. J. Neurogenet., 21: 1–18. 

Bier E, Reiter LT (2002) Using Drosophila melanogaster to uncover human disease gene function and potential drug target proteins. Expert Opin Ther Targets 6:387--399. 

Braff DL, Geyer MA. Sensorimotor gating and schizophrenia:human and animal model studies. Arch Gen Psychiatry 1990; 47:181–188. 

Braff DL, Swerdlow NR, Geyer MA (1995) Gating and habituation deficits in the schizophrenia disorders. Clin Neurosci 3:131-139. 

Engel JE, Wu CF (1996) Altered habituation of an identified escape circuit in Drosophila memory mutants. J Neurosci 16:3486-3499. 

Garcia CC, Blair HJ, Seager M, Coulthard A, Tennant S, Buddles M, Curtis A, Goodship JA. (2004) Identification of a mutation in synapsin I, a synaptic vesicle protein, in a family with epilepsy. J Med Genet 41:183-6. 

Geyer MA, Krebs-Thomson K, Braff DL, Swerdlow NR (2001) Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl) 156:117-154. 

Godenschwege TA, Reisch D, Diegelmann S, Eberle K, Funk N, Heisenberg M, Hoppe V, Hoppe J, Klagges BR, Martin JR, Nikitina EA, Putz G, Reifegerste R, Reisch N, Rister J, Schaupp M, Scholz H, Schwarzel M, Werner U, Zars TD, Buchner S, Buchner E. (2004) Flies lacking all synapsins are unexpectedly healthy but are impaired in complex behaviour. Eur J Neurosci 20:611-22. 

Harrison PJ, Weinberger DR (2005) Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry10:40-68. 

Smith DP (2002) Novel genomic cDNA hybrids produce effective RNA interference in adult Drosophila. Neuron 33:177-84. 

Lease KA, Hirsh J (2005) A novel method of cocaine delivery to fruit flies using a graphic arts airbrush. J Neurosci Methods 141:89-96. 

Matthews AK, Kaufman TC and Gelbart WM (2005) Research resources for Drosophila: The expanding universe. Nature Reviews Genetics 6:179-193. 

Neckameyer WS (1998) Dopamine and mushroom bodies in Drosophila: Experience-dependent and -independent aspects of sexual behavior. Learning Memory 51:157--165. 

Ogden CA, Rich ME, Schork NJ, Paulus MP, Geyer MA, Lohr JB, Kuczenski R, Niculescu AB. (2004) Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Mol Psychiatry 9:1007-29. 

Pendleton RG, Parvez F, Sayed M, Hillman R (2002) Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster. J Pharmacol Exp Therapeutics 300:91--96. 

Scott R, Bourtchuladze R, Gossweiler S, Dubnau J, Tully T (2002) CREB and the discovery of cognitive enhancers. J Mol Neurosci 19:171-177. 

Sharma P, Keane J, O’Kane CJ, Asztalos Z (2007) Automated measurement of Drosophila jump reflex habituation and its use for large-scale behavioural screens for learning and memory mutants. In Preparation. 

Tickoo S, Russell S (2002) Drosophila melanogaster as a model system for drug discovery and pathway screening. Curr Opin Pharmacol 2:555--560. 

Vawter MP, Thatcher L, Usen N, Hyde TM, Kleinman JE, Freed WJ (2002) Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia. Mol Psychiatry 7:571–578. 

Wittekind NC, Spatz HC (1988) Habituation of the landing response of Drosophila. NATO ASI Series, Vol. H19, (Ed. Spazt, Hertting) 1988:351-368.