Aktogen

Publications

Research Papers 

Asztalos, Z., Lossos, M. and Friedrich, P. (1991). On the pharmacological phenocopying of memory-mutants in Drosophila: Alkylxanthines accelerate memory decay. Behav. Genet. 21, 495-511. 

Asztalos, Z., von Wegerer, J., Wustmann, G., Dombradi, V., Gausz, J., Spatz, H.-Ch. and Friedrich, P. (1993) Protein phosphatase 1-deficient mutant Drosophila affected in habituation and associative learning. J. Neurosci. 13, 924-930. 

Lukacsovich, T., Asztalos, Z., Juni, N., Awano, W. and Yamamoto, D. (1999) The Drosophila melanogaster 60A chromosomal division is extremely dense with functional genes: their sequences, genomic organization and expression. Genomics 57, 43-56. 

Nilsson, E., Asztalos, Z., Lukacsovich, T., Awano, W., Ito, K. and Yamamoto, D. (2000) fruitless is in the regulatory pathway by which ectopic mini-white and transformer induce bisexual courtship in Drosophila.. Journal of Neurogenetics, 13, 213-232. 

Lukacsovich, T., Asztalos, Z., Awano, W., Baba, K., Kondo, S., Niwa, S. and Yamamoto, D. (2001) Dual tagging gene-trap of novel genes in Drosophila melanogaster. Genetics 157(2): 727-742. 

Lukacsovich, T., Yuge, K., Awano, W., Asztalos, Z., Kondo, S. Juni, N. and Yamamoto, D. (2003) The ken and barbie gene encoding a putative transcription factor with a BTB domain and three zinc finger motifs functions in terminalia development of Drosophila. Arch. Insect Biochem. Physiol. 54(2): 77-94. 

Ryder, E., Blows, F., Ashburner, M., Bautista-Llacer, R., Coulson, D., Drummond, J., Webster, J., Gubb, D., Gunton, N., Johnson, G., O'Kane, C.J., Huen, D., Sharma, P., Asztalos, Z., Baisch, H., Schulze, J., Kube, M., Kittlaus, K., Reuter, G., Maroy, P., Szidonya, J., Rasmuson-Lestander, A., Ekstrom, K., Dickson, B., Hugentobler, C., Stocker, H., Hafen, E., Lepesant, J.A., Pflugfelder, G., Heisenberg, M., Mechler, B., Serras, F., Corominas, M., Schneuwly, S., Preat, T., Roote, J., Russell, S (2004) The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics 167(2): 797-813. 

Panchal, P.*, Asztalos, Z.*†, Ayyub, de Bruyne, M., Dornan, A. J., Gomez, A., Keane, J., Killeen, J., Kramer, S., Madhavan, M., Roe, H., Dagadu Sherkhane, P., Siddiqi, K., Silva, E., Carlson, J. R., Goodwin, S., Heisenberg, M., Krishnan, K., Kyriacou, C. P., Partridge, L., Riesgo-Escovar, J., Rodrigues, V., Tully, T. and O'Kane, C. † (2005) Isogenic autosomes to be applied in optimal screening for novel mutants with viable phenotypes in Drosophila melanogaster. J. Neurogenet. 19: 57-85. 

Asztalos, Z., Arora, N. and Tully, T. (2007) Olfactory Jump Reflex Habituation In Drosophila and Effects of Classical Conditioning Mutations. J. Neurogenet. 21: 1–18. 

Asztalos, Z., Baba, K., Yamamoto, D. and Tully, T. (2007) The fickle mutation of a cytoplasmic tyrosine kinase effects sensitization but not dishabituation in Drosophila melanogaster. J. Neurogenet. 21: 59–71. 

Joiner, M. A., Asztalos, Z., Jones C., Tully, T. and Wu, C.-F.(2007) Effects of mutant Drosophila K+ Channel Subunits on Habituation of the Olfactory Jump Response. J. Neurogenet. 21: 45–58. 

Sharma, P., Keane, J., O’Kane, C. and Asztalos, Z. (2007) Automated measurement of Drosophila jump reflex habituation and its use for large-scale behavioural screens for learning and memory mutants. Submitted. 

Review Articles 

O’Kane, C. and Asztalos, Z. (1999) Sexual behaviour: Courting dissatisfaction. Current Biology 8, R289-R292. 

Lukacsovich, T., Asztalos, Z. and Yamamoto, D. (2000) Functional Genomics in Drosophila melanogaster by Gene-Trapping. Current Genomics, 1(4), 323-338. 

Selected Abstracts 

Panchal, P., Keane, J., Silva, E., Tully, T., O’Kane, C. and Asztalos, Z. (2002) A semi-automated assay for a simple learning paradigm, jump reflex habituation, and isogenised genetic backgrounds for mutant screens in Drosophila. J. Neurogenet. 

Asztalos, Z., Sharma, P., Gattis, J., Long, P. and O’Kane, C. (2002) A novel habituation mutant has a P insertion in the gene for a novel predicted transmembrane protein. Poster presented at NEUROFLY 2002. 

Lone, G.M., Asztalos, Z., Auburn, R., Bottenberg, W., Kammerer, R., Kane, C.O., Rocha, J., Sweeney, S.T., Yang, M., Prokop, A. (2006). Discovery and Characterisation of Genes involved in de novo formation of Drosophila NMJs. A. Dros. Res. Conf. 47:24. 

Patent 

Lukacsovich, T., Asztalos, Z., Yamamoto, D., Awano, W. (1999) A vector for gene trap, and a method for gene trapping by using the vector. World Patent 1999. 12. 2. WO0996 1604A2.

Publications

Research Papers 

Asztalos, Z., Lossos, M. and Friedrich, P. (1991). On the pharmacological phenocopying of memory-mutants in Drosophila: Alkylxanthines accelerate memory decay. Behav. Genet. 21, 495-511. 

Asztalos, Z., von Wegerer, J., Wustmann, G., Dombradi, V., Gausz, J., Spatz, H.-Ch. and Friedrich, P. (1993) Protein phosphatase 1-deficient mutant Drosophila affected in habituation and associative learning. J. Neurosci. 13, 924-930. 

Lukacsovich, T., Asztalos, Z., Juni, N., Awano, W. and Yamamoto, D. (1999) The Drosophila melanogaster 60A chromosomal division is extremely dense with functional genes: their sequences, genomic organization and expression. Genomics 57, 43-56. 

Nilsson, E., Asztalos, Z., Lukacsovich, T., Awano, W., Ito, K. and Yamamoto, D. (2000) fruitless is in the regulatory pathway by which ectopic mini-white and transformer induce bisexual courtship in Drosophila.. Journal of Neurogenetics, 13, 213-232. 

Lukacsovich, T., Asztalos, Z., Awano, W., Baba, K., Kondo, S., Niwa, S. and Yamamoto, D. (2001) Dual tagging gene-trap of novel genes in Drosophila melanogaster. Genetics 157(2): 727-742. 

Lukacsovich, T., Yuge, K., Awano, W., Asztalos, Z., Kondo, S. Juni, N. and Yamamoto, D. (2003) The ken and barbie gene encoding a putative transcription factor with a BTB domain and three zinc finger motifs functions in terminalia development of Drosophila. Arch. Insect Biochem. Physiol. 54(2): 77-94. 

Ryder, E., Blows, F., Ashburner, M., Bautista-Llacer, R., Coulson, D., Drummond, J., Webster, J., Gubb, D., Gunton, N., Johnson, G., O'Kane, C.J., Huen, D., Sharma, P., Asztalos, Z., Baisch, H., Schulze, J., Kube, M., Kittlaus, K., Reuter, G., Maroy, P., Szidonya, J., Rasmuson-Lestander, A., Ekstrom, K., Dickson, B., Hugentobler, C., Stocker, H., Hafen, E., Lepesant, J.A., Pflugfelder, G., Heisenberg, M., Mechler, B., Serras, F., Corominas, M., Schneuwly, S., Preat, T., Roote, J., Russell, S (2004) The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics 167(2): 797-813. 

Panchal, P.*, Asztalos, Z.*†, Ayyub, de Bruyne, M., Dornan, A. J., Gomez, A., Keane, J., Killeen, J., Kramer, S., Madhavan, M., Roe, H., Dagadu Sherkhane, P., Siddiqi, K., Silva, E., Carlson, J. R., Goodwin, S., Heisenberg, M., Krishnan, K., Kyriacou, C. P., Partridge, L., Riesgo-Escovar, J., Rodrigues, V., Tully, T. and O'Kane, C. † (2005) Isogenic autosomes to be applied in optimal screening for novel mutants with viable phenotypes in Drosophila melanogaster. J. Neurogenet. 19: 57-85. 

Asztalos, Z., Arora, N. and Tully, T. (2007) Olfactory Jump Reflex Habituation In Drosophila and Effects of Classical Conditioning Mutations. J. Neurogenet. 21: 1–18. 

Asztalos, Z., Baba, K., Yamamoto, D. and Tully, T. (2007) The fickle mutation of a cytoplasmic tyrosine kinase effects sensitization but not dishabituation in Drosophila melanogaster. J. Neurogenet. 21: 59–71. 

Joiner, M. A., Asztalos, Z., Jones C., Tully, T. and Wu, C.-F.(2007) Effects of mutant Drosophila K+ Channel Subunits on Habituation of the Olfactory Jump Response. J. Neurogenet. 21: 45–58. 

Sharma, P., Keane, J., O’Kane, C. and Asztalos, Z. (2007) Automated measurement of Drosophila jump reflex habituation and its use for large-scale behavioural screens for learning and memory mutants. Submitted. 

Review Articles 

O’Kane, C. and Asztalos, Z. (1999) Sexual behaviour: Courting dissatisfaction. Current Biology 8, R289-R292. 

Lukacsovich, T., Asztalos, Z. and Yamamoto, D. (2000) Functional Genomics in Drosophila melanogaster by Gene-Trapping. Current Genomics, 1(4), 323-338. 

Selected Abstracts 

Panchal, P., Keane, J., Silva, E., Tully, T., O’Kane, C. and Asztalos, Z. (2002) A semi-automated assay for a simple learning paradigm, jump reflex habituation, and isogenised genetic backgrounds for mutant screens in Drosophila. J. Neurogenet. 

Asztalos, Z., Sharma, P., Gattis, J., Long, P. and O’Kane, C. (2002) A novel habituation mutant has a P insertion in the gene for a novel predicted transmembrane protein. Poster presented at NEUROFLY 2002. 

Lone, G.M., Asztalos, Z., Auburn, R., Bottenberg, W., Kammerer, R., Kane, C.O., Rocha, J., Sweeney, S.T., Yang, M., Prokop, A. (2006). Discovery and Characterisation of Genes involved in de novo formation of Drosophila NMJs. A. Dros. Res. Conf. 47:24. 

Patent 

Lukacsovich, T., Asztalos, Z., Yamamoto, D., Awano, W. (1999) A vector for gene trap, and a method for gene trapping by using the vector. World Patent 1999. 12. 2. WO0996 1604A2.